A brief comparison of polygenic risk scores and Mendelian randomisation

Abstract Mendelian randomisation and polygenic risk score analysis have become increasingly popular in the last decade due to the advent of large-scale genome-wide association studies. Each approach has valuable applications, some of which are overlapping, yet there are important differences which w...

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Bibliographic Details
Main Authors: Victoria Garfield (Author), Emma L. Anderson (Author)
Format: Book
Published: BMC, 2024-01-01T00:00:00Z.
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245 0 0 |a A brief comparison of polygenic risk scores and Mendelian randomisation 
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520 |a Abstract Mendelian randomisation and polygenic risk score analysis have become increasingly popular in the last decade due to the advent of large-scale genome-wide association studies. Each approach has valuable applications, some of which are overlapping, yet there are important differences which we describe here. 
546 |a EN 
690 |a Mendelian randomisation 
690 |a Polygenic risk scores 
690 |a Genome-wide association studies 
690 |a Horizontal pleiotropy 
690 |a Internal medicine 
690 |a RC31-1245 
690 |a Genetics 
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