Artesunate-, sulfadoxine-, and pyrimethamine-induced cardiotoxicity

Here, we report oral artesunate, sulphadoxine and pyrimethamine (sp) induced cardio toxicity case in a female patient. Artesunate is a highly efficacious and relatively safe antimalarial drug. Common adverse reactions to artemisinin derivatives are mild i.e. nausea, vomiting, anorexia and dizziness...

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Main Authors: Divya Goel (Author), Shafiqa Aslam (Author), Rani Walia (Author), Akshay Sadhotra (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2016-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Divya Goel  |e author 
700 1 0 |a Shafiqa Aslam  |e author 
700 1 0 |a Rani Walia  |e author 
700 1 0 |a Akshay Sadhotra  |e author 
245 0 0 |a Artesunate-, sulfadoxine-, and pyrimethamine-induced cardiotoxicity 
260 |b Wolters Kluwer Medknow Publications,   |c 2016-01-01T00:00:00Z. 
500 |a 2468-838X 
500 |a 2456-1975 
500 |a 10.4103/2456-1975.183288 
520 |a Here, we report oral artesunate, sulphadoxine and pyrimethamine (sp) induced cardio toxicity case in a female patient. Artesunate is a highly efficacious and relatively safe antimalarial drug. Common adverse reactions to artemisinin derivatives are mild i.e. nausea, vomiting, anorexia and dizziness which are seen in majority of the patients. While serious toxic effects of artesunate are less frequent i.e., neutropenia, anemia, hemolysis, elevated liver enzymes, allergic reactions and cardiac effects. Cardiac effects due to artesunate are very rare. This case recalls the artesunate potential to cause myocardial injury. 
546 |a EN 
690 |a Artesunate 
690 |a cardiotoxicity 
690 |a malaria 
690 |a sulfadoxine and pyrimethamine 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n BLDE University Journal of Health Sciences, Vol 1, Iss 1, Pp 54-56 (2016) 
787 0 |n http://www.bldeujournalhs.in/article.asp?issn=2468-838X;year=2016;volume=1;issue=1;spage=54;epage=56;aulast=Goel 
787 0 |n https://doaj.org/toc/2468-838X 
787 0 |n https://doaj.org/toc/2456-1975 
856 4 1 |u https://doaj.org/article/ba186b9824d94d82bed6ec5c25ce623c  |z Connect to this object online.