Verapamil Alleviates Myocardial Ischemia/Reperfusion Injury by Attenuating Oxidative Stress via Activation of SIRT1

• Main Authors: Mi Bao (Author), Weiyi Huang (Author), Yang Zhao (Author), Xinzhe Fang (Author), Yanmei Zhang (Author), Fenfei Gao (Author), Danmei Huang (Author), Bin Wang (Author), Ganggang Shi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myocardial ischemia/reperfusion (I/R) injury is a potential complication of ischemic heart disease after recanalization. One of the primary reasons for I/R injury is the excessive accumulation of reactive oxygen species (ROS) in cardiomyocytes. Verapamil, a classic calcium channel blocker, has the p...