Human skeletal myotubes display a cell-autonomous circadian clock implicated in basal myokine secretion

• Main Authors: Laurent Perrin (Author), Ursula Loizides-Mangold (Author), Svetlana Skarupelova (Author), Pamela Pulimeno (Author), Stephanie Chanon (Author), Maud Robert (Author), Karim Bouzakri (Author), Christine Modoux (Author), Pascale Roux-Lombard (Author), Hubert Vidal (Author), Etienne Lefai (Author), Charna Dibner (Author)
• Format: Book
• Published: Elsevier, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Circadian clocks are functional in all light-sensitive organisms, allowing an adaptation to the external world in anticipation of daily environmental changes. In view of the potential role of the skeletal muscle clock in the regulation of glucose metabolism, we aimed to characterize circa...