The ethical case for placebo control in HIV-cure-related studies with ART interruption
Many studies that seek to cure HIV must ask participants to interrupt their antiretroviral treatment. In such circumstances, is it permissible to include a placebo group in the study? We explain why doing so is a scientific and an ethical necessity, and more benign than imagined.
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Elsevier,
2022-09-01T00:00:00Z.
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001 | doaj_ba3d0be3fc9d4a0db364f45b13a41458 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Monica Magalhaes |e author |
700 | 1 | 0 | |a Daniel R. Kuritzkes |e author |
700 | 1 | 0 | |a Nir Eyal |e author |
245 | 0 | 0 | |a The ethical case for placebo control in HIV-cure-related studies with ART interruption |
260 | |b Elsevier, |c 2022-09-01T00:00:00Z. | ||
500 | |a 2055-6640 | ||
500 | |a 10.1016/j.jve.2022.100084 | ||
520 | |a Many studies that seek to cure HIV must ask participants to interrupt their antiretroviral treatment. In such circumstances, is it permissible to include a placebo group in the study? We explain why doing so is a scientific and an ethical necessity, and more benign than imagined. | ||
546 | |a EN | ||
690 | |a HIV Cure-related studies | ||
690 | |a Human subjects research | ||
690 | |a Research ethics | ||
690 | |a Analytic treatment interruption | ||
690 | |a Placebos | ||
690 | |a Microbiology | ||
690 | |a QR1-502 | ||
690 | |a Public aspects of medicine | ||
690 | |a RA1-1270 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Journal of Virus Eradication, Vol 8, Iss 3, Pp 100084- (2022) | |
787 | 0 | |n http://www.sciencedirect.com/science/article/pii/S205566402200022X | |
787 | 0 | |n https://doaj.org/toc/2055-6640 | |
856 | 4 | 1 | |u https://doaj.org/article/ba3d0be3fc9d4a0db364f45b13a41458 |z Connect to this object online. |