The ethical case for placebo control in HIV-cure-related studies with ART interruption

Many studies that seek to cure HIV must ask participants to interrupt their antiretroviral treatment. In such circumstances, is it permissible to include a placebo group in the study? We explain why doing so is a scientific and an ethical necessity, and more benign than imagined.

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Bibliographic Details
Main Authors: Monica Magalhaes (Author), Daniel R. Kuritzkes (Author), Nir Eyal (Author)
Format: Book
Published: Elsevier, 2022-09-01T00:00:00Z.
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100 1 0 |a Monica Magalhaes  |e author 
700 1 0 |a Daniel R. Kuritzkes  |e author 
700 1 0 |a Nir Eyal  |e author 
245 0 0 |a The ethical case for placebo control in HIV-cure-related studies with ART interruption 
260 |b Elsevier,   |c 2022-09-01T00:00:00Z. 
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500 |a 10.1016/j.jve.2022.100084 
520 |a Many studies that seek to cure HIV must ask participants to interrupt their antiretroviral treatment. In such circumstances, is it permissible to include a placebo group in the study? We explain why doing so is a scientific and an ethical necessity, and more benign than imagined. 
546 |a EN 
690 |a HIV Cure-related studies 
690 |a Human subjects research 
690 |a Research ethics 
690 |a Analytic treatment interruption 
690 |a Placebos 
690 |a Microbiology 
690 |a QR1-502 
690 |a Public aspects of medicine 
690 |a RA1-1270 
655 7 |a article  |2 local 
786 0 |n Journal of Virus Eradication, Vol 8, Iss 3, Pp 100084- (2022) 
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