MODAFINIL INDUCES RAPID-ONSET BEHAVIORAL SENSITIZATION AND CROSS-SENSTIZATION WITH COCAINE IN MICE: IMPLICATIONS FOR THE ADDICTIVE POTENTIAL OF MODAFINIL

• Main Authors: Raphael Wuo-Silva (Author), Daniela Fukushiro (Author), André Hollais (Author), Renan Baldaia (Author), Elisa Kawamoto (Author), Lais F Berro (Author), Thais Yokoyama (Author), Leonardo Lopes-Silva (Author), Carolina Bizerra (Author), Roberta Procópio-Souza (Author), Debora Hashiguchi (Author), Lilian Figueiredo (Author), José L Costa (Author), Roberto Frussa-Filho (Author), Beatriz Monteiro Longo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is substantial controversy about the addictive potential of modafinil, a wake-promoting drug used to treat narcolepsy, proposed as pharmacotherapy for cocaine abuse, and used indiscriminately by healthy individuals due to its positive effects on arousal and cognition. The rapid-onset type of b...