Design, Synthesis, and Antibacterial Screening of Some Novel Heteroaryl-Based Ciprofloxacin Derivatives as DNA Gyrase and Topoisomerase IV Inhibitors

• Main Authors: Lamya H. Al-Wahaibi (Author), Amer A. Amer (Author), Adel A. Marzouk (Author), Hesham A. M. Gomaa (Author), Bahaa G. M. Youssif (Author), Antar A. Abdelhamid (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A novel series of ciprofloxacin hybrids comprising various heterocycle derivatives has been synthesized and structurally elucidated using ¹H NMR, ¹³C NMR, and elementary analyses. Using ciprofloxacin as a reference, compounds <b>1-21</b> were...