Clearing and Masking Agents in Pretargeting Strategies

'Pretargeting' led to increased target-to-background ratios of nanomedicines in short timeframes. However, clearing or masking agents are needed to reach the full potential of pretargeted approaches. This review gives an overview of clearing and masking agents employed in pretargeting stra...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Markus Staudt (Awdur), Matthias M. Herth (Awdur)
Fformat: Llyfr
Cyhoeddwyd: MDPI AG, 2023-03-01T00:00:00Z.
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Disgrifiad
Crynodeb:'Pretargeting' led to increased target-to-background ratios of nanomedicines in short timeframes. However, clearing or masking agents are needed to reach the full potential of pretargeted approaches. This review gives an overview of clearing and masking agents employed in pretargeting strategies in both preclinical and clinical settings and discusses how these agents work.
Disgrifiad o'r Eitem:10.3390/ph16040497
1424-8247