Blockade of endothelial adenosine receptor 2 A suppresses atherosclerosis in vivo through inhibiting CREB-ALK5-mediated endothelial to mesenchymal transition

• Main Authors: Yongfeng Cai (Author), Yaqi Zhou (Author), Qiuhua Yang (Author), Jiean Xu (Author), Qingen Da (Author), Qian Ma (Author), Dingwei Zhao (Author), Tammy Lu (Author), Ha Won Kim (Author), David Fulton (Author), Xuejun Jiang (Author), Neal L. Weintraub (Author), Kunzhe Dong (Author), Suowen Xu (Author), Mei Hong (Author), Zhiping Liu (Author), Yuqing Huo (Author)
• Format: Book
• Published: Elsevier, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cardiovascular diseases (CVDs) are the leading cause of death worldwide, and morbidity and mortality rates continue to rise. Atherosclerosis constitutes the principal etiology of CVDs. Endothelial injury, inflammation, and dysfunction are the initiating factors of atherosclerosis. Recently, we repor...