Identification of small molecule lead compounds for visceral leishmaniasis using a novel ex vivo splenic explant model system.
BACKGROUND: New drugs are needed to treat visceral leishmaniasis (VL) because the current therapies are toxic, expensive, and parasite resistance may weaken drug efficacy. We established a novel ex vivo splenic explant culture system from hamsters infected with luciferase-transfected Leishmania dono...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Public Library of Science (PLoS),
2011-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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