Lung necrosis and neutrophils reflect common pathways of susceptibility to Mycobacterium tuberculosis in genetically diverse, immune-competent mice
Pulmonary tuberculosis (TB) is caused by Mycobacterium tuberculosis in susceptible humans. Here, we infected Diversity Outbred (DO) mice with ∼100 bacilli by aerosol to model responses in a highly heterogeneous population. Following infection, 'supersusceptible', 'susceptible' an...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2015-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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