Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient

Mycophenolate mofetil (MMF) is a commonly used immunosuppressive drug in the management of transplant recipients. Gastrointestinal (GI) toxicity (diarrhea) is the most frequently reported adverse event in MMF-treated transplant patients. MMF-induced Graft versus Host Disease has rarely been reported...

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Bibliographic Details
Main Authors: Sushma Patra (Author), Mukul Vij (Author), B Sukanya (Author), Dharmesh Kapoor (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2012-01-01T00:00:00Z.
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Summary:Mycophenolate mofetil (MMF) is a commonly used immunosuppressive drug in the management of transplant recipients. Gastrointestinal (GI) toxicity (diarrhea) is the most frequently reported adverse event in MMF-treated transplant patients. MMF-induced Graft versus Host Disease has rarely been reported in literature. We report a case of MMF-induced colitis with Graft versus Host Disease-like features, to highlight the importance of high clinical suspicion for its diagnosis, and that appropriate management in such a setting can reduce morbidity and mortality. We also review the relevant literature.
Item Description:0377-4929
10.4103/0377-4929.107792