Epsins Regulate Mouse Embryonic Stem Cell Exit from Pluripotency and Neural Commitment by Controlling Notch Activation
Epsins are part of the internalization machinery pivotal to control clathrin-mediated endocytosis. Here, we report that epsin family members are expressed in mouse embryonic stem cells (mESCs) and that epsin1/2 knockdown alters both mESC exits from pluripotency and their differentiation. Furthermore...
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Main Authors: | Marina Cardano (Author), Jacopo Zasso (Author), Luca Ruggiero (Author), Giuseppina Di Giacomo (Author), Matteo Marcatili (Author), Ottavio Cremona (Author), Luciano Conti (Author) |
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Format: | Book |
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Hindawi Limited,
2019-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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