Anakinra Reduces Epileptogenesis, Provides Neuroprotection, and Attenuates Behavioral Impairments in Rats in the Lithium-Pilocarpine Model of Epilepsy

• Autores principales: Alexandra V. Dyomina (Autor), Olga E. Zubareva (Autor), Ilya V. Smolensky (Autor), Dmitry S. Vasilev (Autor), Maria V. Zakharova (Autor), Anna A. Kovalenko (Autor), Alexander P. Schwarz (Autor), Alexander M. Ischenko (Autor), Aleksey V. Zaitsev (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2020-10-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Temporal lobe epilepsy is a widespread chronic disorder that manifests as spontaneous seizures and is often characterized by refractoriness to drug treatment. Temporal lobe epilepsy can be caused by a primary brain injury; therefore, the prevention of epileptogenesis after a primary event is conside...