Possible Involvement of Akt Activity in Endothelial Dysfunction in Type 2 Diabetic Mice
We investigated the effects of chronic simvastatin treatment on the impaired endothelium-dependent relaxation seen in aortas from type 2 diabetic mice. Starting at 8 weeks of diabetes, simvastatin (10 mg/kg per day) was administered to diabetic mice for 4 weeks. The significantly elevated systolic b...
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Main Authors: | Yasuhiro Takenouchi (Author), Tsuneo Kobayashi (Author), Takayuki Matsumoto (Author), Katsuo Kamata (Author) |
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Format: | Book |
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Elsevier,
2008-01-01T00:00:00Z.
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