Meta-Analysis and Systematic Review of Phenotypic and Genotypic Antimicrobial Resistance and Virulence Factors in <i>Vibrio parahaemolyticus</i> Isolated from Shrimp
This systematic review and meta-analysis investigates the prevalence of <i>Vibrio parahaemolyticus</i>, its virulence factors, antimicrobial resistance (AMR), and its resistance determinants in shrimp. This study was conducted following the Preferred Reporting Items for Systematic Review...
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| Main Authors: | , , , |
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| Format: | Book |
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MDPI AG,
2024-04-01T00:00:00Z.
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| Summary: | This systematic review and meta-analysis investigates the prevalence of <i>Vibrio parahaemolyticus</i>, its virulence factors, antimicrobial resistance (AMR), and its resistance determinants in shrimp. This study was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, to identify and select relevant peer-reviewed articles published between January 2020 and December 2022. The search strategy involved multiple online databases, including Google Scholar, PubMed, ScienceDirect, and Scopus. The inclusion criteria focused on studies that examined <i>V. parahaemolyticus</i> prevalence, virulence factors, and AMR in shrimp from farms to retail outlets. A total of 32 studies were analyzed, revealing a pooled estimate prevalence of <i>V. parahaemolyticus</i> in shrimp at 46.0%, with significant heterogeneity observed. Subgroup analysis highlighted varying prevalence rates across continents, emphasizing the need for further investigation. Virulence factor analysis identified thermostable direct hemolysin (<i>tdh</i>) and <i>tdh</i>-related hemolysin (<i>trh</i>) as the most common. Phenotypic AMR analysis indicated notable resistance to glycopeptides, nitrofurans, and beta-lactams. However, the correlation between antimicrobial usage in shrimp farming and observed resistance patterns was inconclusive. Funnel plots suggested potential publication bias, indicating a need for cautious interpretation of findings. This study underscores the urgency of coordinated efforts to address AMR in <i>V. parahaemolyticus</i> to safeguard public health and to ensure sustainable aquaculture practices. |
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| Item Description: | 10.3390/antibiotics13040370 2079-6382 |