Evaluation of New Antimicrobial Agents Based on <i>tris</i>(1<i>H</i>-Indol-3-yl)methylium Salts: Activity, Toxicity, Suppression of Experimental Sepsis in Mice

• Egile Nagusiak: Alexey S. Trenin (Egilea), Elena B. Isakova (Egilea), Michael I. Treshchalin (Egilea), Vasilisa A. Polozkova (Egilea), Elena P. Mirchink (Egilea), Alexey A. Panov (Egilea), Alexander Y. Simonov (Egilea), Olga P. Bychkova (Egilea), Victor V. Tatarskiy (Egilea), Sergey N. Lavrenov (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The antimicrobial activity and toxicity of three novel synthetic antibacterial agents containing <i>tris</i>(1<i>H</i>-indol-3-yl)methylium fragment were studied in vitro and in vivo. All compounds in vitro revealed high activity (minimal inhibitory concentration (MIC) 0.13-1...