Iron deficiency affects oxygen transport and activates HIF1 signaling pathway to regulate phenotypic transformation of VSMC in aortic dissection

• Main Authors: Yuanyang Chen (Author), Xu Li (Author), Zhiwei Wang (Author), Shun Yuan (Author), Xiaoyan Shen (Author), Xiaoping Xie (Author), Kai Xing (Author), Qingyi Zhu (Author)
• Format: Book
• Published: BMC, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Aortic dissection (AD) is a macrovascular disease which is pathologically characterized by aortic media degeneration.This experiment aims to explore how iron deficiency (ID) affects the function of vascular smooth muscle cell (VSMC) and participates in the occurrence and developm...