A study on green synthesis, characterization of chromium oxide nanoparticles and their enzyme inhibitory potential
The conventional chemical methods of nanoparticles synthesis have been effectively replaced by nanoparticle synthesis mediated by plants. The current study describes the environmental friendly synthesis of chromium oxide nanoparticles (Cr2O3 NPs) using Erythrophleum guineense plant extract. The synt...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Book |
| Published: |
Frontiers Media S.A.,
2022-10-01T00:00:00Z.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_bca8545d02c7426bb89bb2be850cf1b5 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Zainab |e author |
| 700 | 1 | 0 | |a Zainab |e author |
| 700 | 1 | 0 | |a Shujaat Ahmad |e author |
| 700 | 1 | 0 | |a Idrees Khan |e author |
| 700 | 1 | 0 | |a Khalid Saeed |e author |
| 700 | 1 | 0 | |a Hanif Ahmad |e author |
| 700 | 1 | 0 | |a Aftab Alam |e author |
| 700 | 1 | 0 | |a Mazen Almehmadi |e author |
| 700 | 1 | 0 | |a Ahad Amer Alsaiari |e author |
| 700 | 1 | 0 | |a Yu Haitao |e author |
| 700 | 1 | 0 | |a Manzoor Ahmad |e author |
| 245 | 0 | 0 | |a A study on green synthesis, characterization of chromium oxide nanoparticles and their enzyme inhibitory potential |
| 260 | |b Frontiers Media S.A., |c 2022-10-01T00:00:00Z. | ||
| 500 | |a 1663-9812 | ||
| 500 | |a 10.3389/fphar.2022.1008182 | ||
| 520 | |a The conventional chemical methods of nanoparticles synthesis have been effectively replaced by nanoparticle synthesis mediated by plants. The current study describes the environmental friendly synthesis of chromium oxide nanoparticles (Cr2O3 NPs) using Erythrophleum guineense plant extract. The synthesis of Cr2O3 NPs was validated by UV/VIS spectroscopy, Energy Dispersive X-Ray (EDX), Scanning Electron Microscopy (SEM), and X-ray diffraction (XRD) studies. The appearance of the Sharpe peak at 460 nm in the UV/Vis spectrum and the colour change caused by surface plasma resonance confirmed the formation of Cr2O3 NPs. The EDX spectrum of Cr2O3 nanoparticles revealed the presence of carbon, oxygen, and chromium, while SEM analysis revealed an irregular round morphology (with a size below 400 nm). In addition, XRD studies suggested their crystalline nature by the characteristic peaks at 34° and 36° and 42° (2Ɵ), respectively. The green synthesized Cr2O3 NPs showed promise as in-vitro cholinesterase inhibitor at tested concentrations (62.5-1,000 μg/ml), with IC50 values of 120 and 100 μg/ml against Acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE), respectively. The results suggested that the green synthesized Cr2O3 NPs could be used in the future to stop enzyme from working and for other biological activities. | ||
| 546 | |a EN | ||
| 690 | |a chromium oxide nanoparticles | ||
| 690 | |a green synthesis | ||
| 690 | |a enzyme inhibition | ||
| 690 | |a characterization | ||
| 690 | |a cholinesterase inhibition | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Frontiers in Pharmacology, Vol 13 (2022) | |
| 787 | 0 | |n https://www.frontiersin.org/articles/10.3389/fphar.2022.1008182/full | |
| 787 | 0 | |n https://doaj.org/toc/1663-9812 | |
| 856 | 4 | 1 | |u https://doaj.org/article/bca8545d02c7426bb89bb2be850cf1b5 |z Connect to this object online. |