Pigmented variant of pleomorphic xanthoastrocytoma - A rare long-term epilepsy associated neoplasm

Pleomorphic xanthoastrocytoma (PXA) is an uncommon, long-term epilepsy associated tumor of young adults. Its pigmented variant is exceedingly rare, with only five previously reported cases on record. We report the sixth case of pigmented PXA in a 24-year-old lady presenting with long-standing seizur...

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Bibliographic Details
Main Authors: Rajalakshmi Poyuran (Author), Nirupam Moudgil (Author), Arivazhagan Arimappamagan (Author), Rose D Bharath (Author), Anita Mahadevan (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
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Summary:Pleomorphic xanthoastrocytoma (PXA) is an uncommon, long-term epilepsy associated tumor of young adults. Its pigmented variant is exceedingly rare, with only five previously reported cases on record. We report the sixth case of pigmented PXA in a 24-year-old lady presenting with long-standing seizures. The MRI revealed a solid cystic lesion located in the right medial temporal lobe. Histopathologically, the superficially located tumor showed typical features of PXA with melanin-laden astrocytic component and was negative for V600E-mutant BRAF. The histogenesis is discussed.
Item Description:0377-4929
10.4103/IJPM.IJPM_723_18