Novel Biomarkers for the diagnosis of diabetic nephropathy

Diabetes mellitus and its complications are a known public health problem nowadays. Diabetic nephropathy is one of the main complications and the result of multiple mechanisms, including: activation of the renin-angiotensin-aldosterone system, formation of advanced glycation end products and chronic...

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Main Authors: Marcio Concepción-Zavaleta (Author), Juan Quiroz-Aldave (Author), Jacsel Suarez Rojas (Author), José Paz-Ibarra (Author), Pela Roseboom (Author), Sofia Ildefonso-Najarro (Author), Denis Cribilleros Zevallos (Author), Francisca Zavaleta-Gutiérrez (Author), Julia Coronado-Arroyo (Author), Luis Concepción-Urteaga (Author)
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Published: Babol University of Medical Sciences, 2024-05-01T00:00:00Z.
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001 doaj_bcfe616cfc1c4f1eb977e322434e044c
042 |a dc 
100 1 0 |a Marcio Concepción-Zavaleta  |e author 
700 1 0 |a Juan Quiroz-Aldave  |e author 
700 1 0 |a Jacsel Suarez Rojas  |e author 
700 1 0 |a José Paz-Ibarra  |e author 
700 1 0 |a Pela Roseboom  |e author 
700 1 0 |a Sofia Ildefonso-Najarro  |e author 
700 1 0 |a Denis Cribilleros Zevallos  |e author 
700 1 0 |a Francisca Zavaleta-Gutiérrez  |e author 
700 1 0 |a Julia Coronado-Arroyo  |e author 
700 1 0 |a Luis Concepción-Urteaga  |e author 
245 0 0 |a Novel Biomarkers for the diagnosis of diabetic nephropathy 
260 |b Babol University of Medical Sciences,   |c 2024-05-01T00:00:00Z. 
500 |a 2008-6164 
500 |a 2008-6172 
520 |a Diabetes mellitus and its complications are a known public health problem nowadays. Diabetic nephropathy is one of the main complications and the result of multiple mechanisms, including: activation of the renin-angiotensin-aldosterone system, formation of advanced glycation end products and chronic inflammation that led to glomerular and tubulo-interstitial damage producing mesangial expansion and glomerulosclerosis, which finally results in chronic kidney disease. Early detection of diabetic nephropathyis essential for adequate intervention to stop, or at least sloww down its progression. Multiple markers have been described, not only the classic ones such as serum creatinine, urea, and albuminuria, but at this point also novel biomarkers such as neutrophil gelatinase-associated lipocalin, tumor necrosis factor 1 receptor and monocyte chemoattractant protein-1, among others. The aim of this article was to provide an update review of the role of biomarkers in the diagnosis of diabetic nephropathy. 
546 |a EN 
690 |a diabetes mellitus 
690 |a diabetic nephropathy 
690 |a biomarkers 
690 |a diagnosis 
690 |a Internal medicine 
690 |a RC31-1245 
655 7 |a article  |2 local 
786 0 |n Caspian Journal of Internal Medicine, Vol 15, Iss 3, Pp 382-391 (2024) 
787 0 |n http://caspjim.com/article-1-3609-en.pdf 
787 0 |n https://doaj.org/toc/2008-6164 
787 0 |n https://doaj.org/toc/2008-6172 
856 4 1 |u https://doaj.org/article/bcfe616cfc1c4f1eb977e322434e044c  |z Connect to this object online.