ASA Suppresses PGE₂ in Plasma and Melanocytic Nevi of Human Subjects at Increased Risk for Melanoma

• Main Authors: Amir Varedi (Author), Hafeez Rahman (Author), Dileep Kumar (Author), Jonathan L. Catrow (Author), James E. Cox (Author), Tong Liu (Author), Scott R. Florell (Author), Kenneth M. Boucher (Author), Nwanneka Okwundu (Author), William J. Burnett (Author), Matthew W. VanBrocklin (Author), Douglas Grossman (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Potential anti-inflammatory and anticarcinogenic effects of aspirin (ASA) may be suitable for melanoma chemoprevention, but defining biomarkers in relevant target tissues is prerequisite to performing randomized controlled chemoprevention trials. We conducted open-label studies with ASA in 53 human...