Modulatory Effect of 4-(methylthio)butyl Isothiocyanate Isolated From Eruca Sativa Thell. on DMBA Induced Overexpression of Hypoxia and Glycolytic Pathway in Sprague-Dawley Female Rats

• Egile Nagusiak: Davinder Singh (Egilea), Sharad Thakur (Egilea), Drishtant Singh (Egilea), Harpal Singh Buttar (Egilea), Balbir Singh (Egilea), Saroj Arora (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

4-(methylthio)butyl isothiocyanate (4-MTBITC) is a hydrolytic product from the plant Eruca sativa Thell. In the present study, we explored the anti-cancer effect of 4-MTBITC against 7,12-dimethylbenz [a] anthracene (DMBA) induced breast cancer. Hypoxic conditions were developed using a single dose o...