Mean yield pressure from the in-die Heckel analysis is a reliable plasticity parameter

Despite the ability to characterize the plasticity of powders in a material-sparing and expedited manner, the in-die Heckel analysis has been widely criticized for its sensitivity to several factors, such as particle elastic deformation, tooling size, lubrication, and speed. Using materials exhibiti...

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Главные авторы: Gerrit Vreeman (Автор), Changquan Calvin Sun (Автор)
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Опубликовано: Elsevier, 2021-12-01T00:00:00Z.
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100 1 0 |a Gerrit Vreeman  |e author 
700 1 0 |a Changquan Calvin Sun  |e author 
245 0 0 |a Mean yield pressure from the in-die Heckel analysis is a reliable plasticity parameter 
260 |b Elsevier,   |c 2021-12-01T00:00:00Z. 
500 |a 2590-1567 
500 |a 10.1016/j.ijpx.2021.100094 
520 |a Despite the ability to characterize the plasticity of powders in a material-sparing and expedited manner, the in-die Heckel analysis has been widely criticized for its sensitivity to several factors, such as particle elastic deformation, tooling size, lubrication, and speed. Using materials exhibiting a wide range of mechanical properties, we show that the in-die Py correlates strongly with three established plasticity parameters obtained from the out-of-die Heckel analysis, Kuentz-Leuenberger analysis, and macroindentation. Thus, the in-die Py is a reliable parameter for quantifying powder plasticity in a material-sparing and expedited manner. 
546 |a EN 
690 |a Compaction 
690 |a Plasticity 
690 |a Powder 
690 |a Heckel analysis 
690 |a In-die 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100094- (2021) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S2590156721000232 
787 0 |n https://doaj.org/toc/2590-1567 
856 4 1 |u https://doaj.org/article/bd84d15c992841bc9ce3e08aa00abd5c  |z Connect to this object online.