Mean yield pressure from the in-die Heckel analysis is a reliable plasticity parameter
Despite the ability to characterize the plasticity of powders in a material-sparing and expedited manner, the in-die Heckel analysis has been widely criticized for its sensitivity to several factors, such as particle elastic deformation, tooling size, lubrication, and speed. Using materials exhibiti...
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Elsevier,
2021-12-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_bd84d15c992841bc9ce3e08aa00abd5c | ||
042 | |a dc | ||
100 | 1 | 0 | |a Gerrit Vreeman |e author |
700 | 1 | 0 | |a Changquan Calvin Sun |e author |
245 | 0 | 0 | |a Mean yield pressure from the in-die Heckel analysis is a reliable plasticity parameter |
260 | |b Elsevier, |c 2021-12-01T00:00:00Z. | ||
500 | |a 2590-1567 | ||
500 | |a 10.1016/j.ijpx.2021.100094 | ||
520 | |a Despite the ability to characterize the plasticity of powders in a material-sparing and expedited manner, the in-die Heckel analysis has been widely criticized for its sensitivity to several factors, such as particle elastic deformation, tooling size, lubrication, and speed. Using materials exhibiting a wide range of mechanical properties, we show that the in-die Py correlates strongly with three established plasticity parameters obtained from the out-of-die Heckel analysis, Kuentz-Leuenberger analysis, and macroindentation. Thus, the in-die Py is a reliable parameter for quantifying powder plasticity in a material-sparing and expedited manner. | ||
546 | |a EN | ||
690 | |a Compaction | ||
690 | |a Plasticity | ||
690 | |a Powder | ||
690 | |a Heckel analysis | ||
690 | |a In-die | ||
690 | |a Pharmacy and materia medica | ||
690 | |a RS1-441 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100094- (2021) | |
787 | 0 | |n http://www.sciencedirect.com/science/article/pii/S2590156721000232 | |
787 | 0 | |n https://doaj.org/toc/2590-1567 | |
856 | 4 | 1 | |u https://doaj.org/article/bd84d15c992841bc9ce3e08aa00abd5c |z Connect to this object online. |