Pharmacokinetics and metabolism of ketoconazole after single ocular instillation in Sprague-Dawley rats
Background and purpose: Ketoconazole is limited to its conditioned oral use due to hepatic toxicity. Its ocular eye drop administration may be an option for mycotic keratitis treatment. Therefore, it is necessary to explore its pharmacokinetic and metabolic profile via topical ocular administration....
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| Main Authors: | , , , , , |
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| Format: | Book |
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International Association of Physical Chemists (IAPC),
2024-11-01T00:00:00Z.
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