Natural Course of Activated Phosphoinositide 3-Kinase Delta Syndrome in Childhood and Adolescence

• প্রধান লেখক: Marketa Bloomfield (Author), Adam Klocperk (Author), Radana Zachova (Author), Tomas Milota (Author), Veronika Kanderova (Author), Anna Sediva (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Activated phosphoinositide 3-kinase delta syndrome (APDS), caused by mutations in PI3Kδ catalytic p110δ (PIK3CD) or regulatory p85α (PIK3R1) subunits, is a primary immunodeficiency affecting both humoral and cellular immunity, which shares some phenotypic similarities with hyper-IgM syndromes and co...