Hepatotoxicity of the Major Anthraquinones Derived From Polygoni Multiflori Radix Based on Bile Acid Homeostasis

• Main Authors: Li Kang (Author), Dan Li (Author), Xin Jiang (Author), Yao Zhang (Author), Minhong Pan (Author), Yixin Hu (Author), Luqin Si (Author), Yongjun Zhang (Author), Jiangeng Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Polygoni Multiflori Radix (PMR), the dried root of Polygonum Multiflorum Thunb., has been widely used as traditional Chinese medicines in clinical practice for centuries. However, the frequently reported hepatotoxic adverse effects hindered its safe use in clinical practice. This study aims to explo...