Promising Effects of Casearins in Tumor-Bearing Mice and Antinociceptive Action against Oncologic Pain: Molecular Docking and In Vivo Findings

• Main Authors: Jurandy do Nascimento Silva (Author), José Ivo Araújo Beserra Filho (Author), Boris Timah Acha (Author), Fernanda Regina de Castro Almeida (Author), Emanuelle Karine Frota Batista (Author), Valdenizia Rodrigues Silva (Author), Larissa Mendes Bomfim (Author), Milena Botelho Pereira Soares (Author), Daniel Pereira Bezerra (Author), André Gonzaga dos Santos (Author), Francisco das Chagas Pereira de Andrade (Author), Anderson Nogueira Mendes (Author), Daniel Dias Rufino Arcanjo (Author), Paulo Michel Pinheiro Ferreira (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Safer analgesic drugs remain a hard challenge because of cardiovascular and/or gastrointestinal toxicity, mainly. So, this study evaluated in vivo the antiproliferative actions of a fraction with casearins (FC) from <i>Casearia sylvestris</i> leaves against human colorectal carcinomas an...