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: A Novel ROS1 Oncogenic Fusion Detected on Next Generation Sequencing

Advanced Non-Small Cell Lung Carcinoma (NSCLC) patients with ROS1 gene rearrangement have shown significant therapeutic responses to tyrosine kinase inhibitors approved by the US Food and Drug Administration, with approximately 40 fusion partners documented in the existing literature. Our report hig...

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Main Authors: Anurag Mehta (Author), Himanshi Diwan (Author), Shrinidhi Nathany (Author), Ullas Batra (Author), Manoj Gupta (Author), Manoj Kumar Panigrahi (Author), Dushyant Kumar (Author), Sakshi Mattoo (Author), Aayushi Singh (Author)
Format: Book
Published: SAGE Publishing, 2024-08-01T00:00:00Z.
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Summary:Advanced Non-Small Cell Lung Carcinoma (NSCLC) patients with ROS1 gene rearrangement have shown significant therapeutic responses to tyrosine kinase inhibitors approved by the US Food and Drug Administration, with approximately 40 fusion partners documented in the existing literature. Our report highlights a novel fusion partner of ROS1 that has demonstrated a conclusive response to the current standard of treatment.
Item Description:2632-010X
10.1177/2632010X241269373

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