Hippocampal Endoplasmic Reticulum Stress Hastens Motor and Cognitive Decline in Adult Male Rats Sustainedly Exposed to High-Sucrose Diet

• Main Authors: Bruno Araújo Serra Pinto (Author), Thamys Marinho Melo (Author), Karla Frida Torres Flister (Author), Lucas Martins França (Author), Vanessa Ribeiro Moreira (Author), Daniela Kajihara (Author), Nelmar Oliveira Mendes (Author), Silma Regina Pereira (Author), Francisco Rafael Martins Laurindo (Author), Antonio Marcus Andrade Paes (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metabolic dysfunctions, such as hyperglycemia and insulin resistance, have been associated to cognitive impairment and dementia regardless of advanced age, although the underlying mechanisms are still elusive. Thus, this study investigates the deleterious effects of metabolic syndrome (MetS) induced...