Stability of Bendamustine Solutions: Influence of Sodium Chloride Concentration, Temperature and Container
Bendamustine is used for the treatment of non-Hodgkin lymphoma, chronic lymphocytic leukaemia and myeloma. The stability of bendamustine is highly dependent on temperature and chloride-ion concentration. Limited stability data are available. The objective of this work was to study the stability of t...
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| Main Authors: | , , |
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| Format: | Book |
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De Gruyter,
2018-03-01T00:00:00Z.
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| Summary: | Bendamustine is used for the treatment of non-Hodgkin lymphoma, chronic lymphocytic leukaemia and myeloma. The stability of bendamustine is highly dependent on temperature and chloride-ion concentration. Limited stability data are available. The objective of this work was to study the stability of the bendamustine reconstituted solution at 2.5 mg/mL and the diluted solution in normal saline and 1.5 % sodium chloride to evaluate a potential increase in stability. |
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| Item Description: | 2365-2411 2365-242X 10.1515/pthp-2017-0033 |