Hsp90 Inhibitors and the Reduction of Anti-Cancer Drug Resistance by Non-Genetic and Genetic Mechanisms
In this review, we focus on how inhibitors of Hsp90 can help prevent the resistance to anti-cancer drugs by synergistically increasing their cancer killing abilities and thereby allowing them to function at much lower concentrations than normally used. Hsp90 helps to fold numerous client proteins, s...
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Main Authors: | Douglas M. Ruden (Author), Xiangyi Lu (Author), Luan Wang (Author) |
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Format: | Book |
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MDPI AG,
2012-08-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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