Acute Liver Failure in Patients with Classic Heat Stroke

Background: Classic heat stroke is defined by a core temperature greater than 40° C, severe dehydration and neurological alterations. Patients with liver disease due to heat stroke have been described, mostly by exercise. Hepatic failure is defined as the presence of a coagulopathy accompanied by an...

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Main Authors: Jeremy J. Hernández-Ríos (Author), Fátima María Martínez-González (Author), Luz A. Gutiérrez-Bañales (Author), J. Andrés Beltrán-López (Author), Hiram J. Jaramillo-Ramírez (Author)
Format: Book
Published: University Library System, University of Pittsburgh, 2020-08-01T00:00:00Z.
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Summary:Background: Classic heat stroke is defined by a core temperature greater than 40° C, severe dehydration and neurological alterations. Patients with liver disease due to heat stroke have been described, mostly by exercise. Hepatic failure is defined as the presence of a coagulopathy accompanied by any degree of hepatic encephalopathy. The primary objective of the study lies in the fact that patients who developed acute liver failure during their hospital stay had a higher risk of mortality. Methods: A retrospective, analytical study of patients admitted to the General Hospital of Mexicali who suffered from classic heat stroke from March 2006 through August 2010, and a second period from June 2018 to August 2019. Results: Fifty patients were recruited, the group included 48 (96%) male, with a total of 10 fatalities, representing 20%. INR greater than 1.5, AST and ALT levels were not related to an increased mortality rate. Conclusion: Neither transaminase levels, nor liver failure, were related to a higher mortality rate in this cohort of patients with classic heat stroke.
Item Description:10.5195/ijms.2020.442
2076-6327