IFN-γ in ovarian tumor microenvironment upregulates HLA-E expression and predicts a poor prognosis

• المؤلفون الرئيسيون: Hui Zheng (مؤلف), Xiaolin Guan (مؤلف), Xin Meng (مؤلف), Ying Tong (مؤلف), Yanchun Wang (مؤلف), Suhong Xie (مؤلف), Lin Guo (مؤلف), Renquan Lu (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2023-11-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Inflammation and immunity are two main characteristics of tumor microenvironment (TME). Interferon-gamma (IFN-γ) is generally considered as a pro-inflammatory cytokine which mediates anti-tumor immune response. Recently, IFN-γ was also reported to play a protumorigenic role. Howe...