Lung function measurements in rodents in safety pharmacology studies
The ICH guideline S7A requires safety pharmacology tests including measurements of pulmonary function. In the first step - as part of the core battery - lung function tests in conscious animals are requested. If potential adverse effects raise concern for human safety, these should be explored in a...
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Frontiers Media S.A.,
2012-08-01T00:00:00Z.
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