Multi-omics characterization of silent and productive HPV integration in cervical cancer

• Main Authors: Junpeng Fan (Author), Yu Fu (Author), Wenju Peng (Author), Xiong Li (Author), Yuanming Shen (Author), Ensong Guo (Author), Funian Lu (Author), Shengtao Zhou (Author), Si Liu (Author), Bin Yang (Author), Xu Qin (Author), Dianxing Hu (Author), Rourou Xiao (Author), Xi Li (Author), Siqi Yang (Author), Cunzhong Yuan (Author), Yao Shu (Author), He Huang (Author), Ting Wan (Author), Yanan Pi (Author), Shuxiang Wang (Author), Wenjuan Chen (Author), Haixia Wang (Author), Lin Zhong (Author), Li Yuan (Author), Baogang Wen (Author), Beihua Kong (Author), Gordon B. Mills (Author), Dongling Zou (Author), Bairong Xia (Author), Kun Song (Author), Gang Chen (Author), Ding Ma (Author), Chaoyang Sun (Author)
• Format: Book
• Published: Elsevier, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Cervical cancer (CC) that is caused by high-risk human papillomavirus (HPV) remains a significant public health problem worldwide. HPV integration sites can be silent or actively transcribed, leading to the production of viral-host fusion transcripts. Herein, we demonstrate that only produc...