The state of the cytokine profile under the conditions of the immobilization stress development

The aim of our study is to elucidate changes in the content of pro-inflammatory interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) and anti-inflammatory cytokines interleukin-10 (IL-10) in the blood serum of guinea pigs in the dynamics of experimental immobilization stress.The dynamics of the...

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Main Authors: P. Olekshij (Author), M. Regeda (Author), I. Hayduchok (Author)
Format: Book
Published: Kazimierz Wielki University, 2023-08-01T00:00:00Z.
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042 |a dc 
100 1 0 |a P. Olekshij  |e author 
700 1 0 |a M. Regeda  |e author 
700 1 0 |a I. Hayduchok  |e author 
245 0 0 |a The state of the cytokine profile under the conditions of the immobilization stress development 
260 |b Kazimierz Wielki University,   |c 2023-08-01T00:00:00Z. 
500 |a 10.12775/JEHS.2023.47.01.006 
500 |a 2391-8306 
520 |a The aim of our study is to elucidate changes in the content of pro-inflammatory interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) and anti-inflammatory cytokines interleukin-10 (IL-10) in the blood serum of guinea pigs in the dynamics of experimental immobilization stress.The dynamics of the immobilization stress is accompanied by a pronounced progression of the proinflammatory group of cytokines - TNF-α and IL-6 against the background of declining functional activity of IL-10 at all stages of their formation (3 rd, 5 th and 15 th days) with an advantage on the 3 rd day of the experiment. The data obtained indicate an imbalance of pro- and anti-inflammatory cytokines and impaired cytokinogenesis, which is important for the pathogenesis in immobilization stress. 
546 |a EN 
546 |a ES 
546 |a PL 
546 |a RU 
546 |a UK 
690 |a immobilization stress 
690 |a tumor necrosis factor - α 
690 |a interleukins 
690 |a cytokines 
690 |a Education 
690 |a L 
690 |a Sports 
690 |a GV557-1198.995 
690 |a Medicine 
690 |a R 
655 7 |a article  |2 local 
786 0 |n Journal of Education, Health and Sport, Vol 47, Iss 1 (2023) 
787 0 |n https://apcz.umk.pl/JEHS/article/view/46135 
787 0 |n https://doaj.org/toc/2391-8306 
856 4 1 |u https://doaj.org/article/c04a23eb08c848aa8a00c3e3d6822c1a  |z Connect to this object online.