The state of the cytokine profile under the conditions of the immobilization stress development
The aim of our study is to elucidate changes in the content of pro-inflammatory interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) and anti-inflammatory cytokines interleukin-10 (IL-10) in the blood serum of guinea pigs in the dynamics of experimental immobilization stress.The dynamics of the...
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Kazimierz Wielki University,
2023-08-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_c04a23eb08c848aa8a00c3e3d6822c1a | ||
042 | |a dc | ||
100 | 1 | 0 | |a P. Olekshij |e author |
700 | 1 | 0 | |a M. Regeda |e author |
700 | 1 | 0 | |a I. Hayduchok |e author |
245 | 0 | 0 | |a The state of the cytokine profile under the conditions of the immobilization stress development |
260 | |b Kazimierz Wielki University, |c 2023-08-01T00:00:00Z. | ||
500 | |a 10.12775/JEHS.2023.47.01.006 | ||
500 | |a 2391-8306 | ||
520 | |a The aim of our study is to elucidate changes in the content of pro-inflammatory interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) and anti-inflammatory cytokines interleukin-10 (IL-10) in the blood serum of guinea pigs in the dynamics of experimental immobilization stress.The dynamics of the immobilization stress is accompanied by a pronounced progression of the proinflammatory group of cytokines - TNF-α and IL-6 against the background of declining functional activity of IL-10 at all stages of their formation (3 rd, 5 th and 15 th days) with an advantage on the 3 rd day of the experiment. The data obtained indicate an imbalance of pro- and anti-inflammatory cytokines and impaired cytokinogenesis, which is important for the pathogenesis in immobilization stress. | ||
546 | |a EN | ||
546 | |a ES | ||
546 | |a PL | ||
546 | |a RU | ||
546 | |a UK | ||
690 | |a immobilization stress | ||
690 | |a tumor necrosis factor - α | ||
690 | |a interleukins | ||
690 | |a cytokines | ||
690 | |a Education | ||
690 | |a L | ||
690 | |a Sports | ||
690 | |a GV557-1198.995 | ||
690 | |a Medicine | ||
690 | |a R | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Journal of Education, Health and Sport, Vol 47, Iss 1 (2023) | |
787 | 0 | |n https://apcz.umk.pl/JEHS/article/view/46135 | |
787 | 0 | |n https://doaj.org/toc/2391-8306 | |
856 | 4 | 1 | |u https://doaj.org/article/c04a23eb08c848aa8a00c3e3d6822c1a |z Connect to this object online. |