Pharmacokinetics of Orally Administered Poly(Ethylene Oxide)-block-Poly(ε-Caprolactone) Micelles of Cyclosporine A in Rats: Comparison with Neoral®

• Main Authors: Ziyad Binkhathlan (Author), Raisuddin Ali (Author), Wajhul Qamar (Author), Afsaneh Lavasanifar (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2018-08-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

PURPOSE: The aim of this study was to assess the pharmacokinetics of methoxy poly(ethylene oxide)-block-poly(ε-caprolactone) (PEO-b-PCL) micellar formulation of cyclosporine A (CyA) following oral administration in rats making comparisons with its commercial microemulsion formulation, Neoral®. METHO...