Purely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide

Langerhans cell histiocytosis (LCH) is a rare, clonal proliferative disorder of Langerhans' cells of unknown etiology. Although the clinical presentation and therapeutic approach to the disease in children have been well established; limited data is available about the disease in adults. Purely...

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Bibliographic Details
Main Authors: Radhakrishnan Subramaniyan (Author), Rajagopal Ramachandran (Author), Gnanasekaran Rajangam (Author), Navya Donaparthi (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2015-01-01T00:00:00Z.
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Summary:Langerhans cell histiocytosis (LCH) is a rare, clonal proliferative disorder of Langerhans' cells of unknown etiology. Although the clinical presentation and therapeutic approach to the disease in children have been well established; limited data is available about the disease in adults. Purely cutaneous involvement of LCH in a man older than 70 years has rarely been described. Herein we report the case of a 71-year-old man with cutaneous LCH confined to the perioral region, scalp, and flexures successfully treated with thalidomide.
Item Description:2229-5178
10.4103/2229-5178.169743