Deep vein thrombosis - the review

• Huvudupphovsmän: Karol Stępniak (Författare, medförfattare), Wiktor Telega (Författare, medförfattare), Kinga Wnuczek (Författare, medförfattare), Joanna Wrona (Författare, medförfattare), Aleksandra Kaźmierczyk (Författare, medförfattare), Jędrzej Kęsik (Författare, medförfattare), Daria Madycka (Författare, medförfattare), Kacper Michta (Författare, medförfattare), Małgorzata Słaboń (Författare, medförfattare), Maciej Sobczyk (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: Nicolaus Copernicus University in Toruń, 2024-11-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

Sammanfattning

Deep vein thrombosis impacts between 2.5% and 5% of a population. It mostly affects lower-extremity veins and presents itself as pain, swelling, tenderness, and erythema of an affected region. Thrombus forms when at least one factor from the Virchow's triad is present - vascular damage, venous stasis or hypercoagulability. A range of clinical manifestations is very wide, from asymptomatic to life-threatening course of the disease. Post-thrombotic syndrome is a frequent complication that results in venous hypertension, which leads to tissue edema, subcutaneous fibrosis, and subsequent ulceration. In the diagnostic process, predominantly D-dimer assay and ultrasonographic compression test are performed. Noninvasive treatment relies on anticoagulation therapy which is based on direct oral anticoagulants, parenteral anticoagulants, and vitamin K antagonists. In specific cases, there is an option of invasive treatment, which involves inserting a catheter into a vein with a thrombus. Afterward, a thrombus can be mechanically fragmented and aspired or dissolved with the use of a thrombolytic agent. 

Beskrivning

10.12775/QS.2024.34.56187
2450-3118