Nobiletin Inhibits Cell Viability via the SRC/AKT/STAT3/YY1AP1 Pathway in Human Renal Carcinoma Cells

• Main Authors: Di Wei (Author), Geng Zhang (Author), Zheng Zhu (Author), Yu Zheng (Author), Fei Yan (Author), Chongxian Pan (Author), Zhiyong Wang (Author), Xian Li (Author), Fuli Wang (Author), Ping Meng (Author), Wanxiang Zheng (Author), Zhao Yan (Author), Dongsheng Zhai (Author), Zifan Lu (Author), Jianlin Yuan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nobiletin is a polymethoxy flavonoid isolated from Citrus depressa and Citrus reticulata. It has been reported that nobiletin can suppress tumors. We primarily explored the antitumor effects of nobiletin and the associated potential mechanisms in ACHN and Caki-2 renal carcinoma cells. A CCK-8 assay...