Efficient Transdermal Delivery of Alendronate, a Nitrogen-Containing Bisphosphonate, Using Tip-Loaded Self-Dissolving Microneedle Arrays for the Treatment of Osteoporosis
To improve the transdermal bioavailability and safety of alendronate (ALN), a nitrogen-containing bisphosphonate, we developed self-dissolving microneedle arrays (MNs), in which ALN is loaded only at the tip portion of micron-scale needles by a dip-coating method (ALN(TIP)-MN). We observed micron-sc...
Saved in:
Main Authors: | Hidemasa Katsumi (Author), Yutaro Tanaka (Author), Kaori Hitomi (Author), Shu Liu (Author), Ying-shu Quan (Author), Fumio Kamiyama (Author), Toshiyasu Sakane (Author), Akira Yamamoto (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2017-08-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Self-Dissolving Microneedle Arrays for Transdermal Absorption Enhancement of Human Parathyroid Hormone (1-34)
by: Chihiro Naito, et al.
Published: (2018) -
Levothyroxine sodium loaded dissolving microneedle arrays for transdermal delivery
by: Riyam Faisal Ghazi, et al.
Published: (2022) -
Nanosuspension-Based Dissolving Microneedle Arrays for Intradermal Delivery of Curcumin
by: Sharif Abdelghany, et al.
Published: (2019) -
Development of Novel Faster-Dissolving Microneedle Patches for Transcutaneous Vaccine Delivery
by: Akihiko Ono, et al.
Published: (2017) -
Nanosuspension-Based Dissolvable Microneedle Arrays to Enhance Diclofenac Skin Delivery
by: Luca Casula, et al.
Published: (2023)