PTHrP promotes subchondral bone formation in TMJ-OA

• Main Authors: Jun Zhang (Author), Caixia Pi (Author), Chen Cui (Author), Yang Zhou (Author), Bo Liu (Author), Juan Liu (Author), Xin Xu (Author), Xuedong Zhou (Author), Liwei Zheng (Author)
• Format: Book
• Published: Nature Publishing Group, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract PTH-related peptide (PTHrP) improves the bone marrow micro-environment to activate the bone-remodelling, but the coordinated regulation of PTHrP and transforming growth factor-β (TGFβ) signalling in TMJ-OA remains incompletely understood. We used disordered occlusion to establish model anim...