Carveol a Naturally-Derived Potent and Emerging Nrf2 Activator Protects Against Acetaminophen-Induced Hepatotoxicity

• Main Authors: Zaif Ur Rahman (Author), Lina Tariq Al Kury (Author), Abdullah Alattar (Author), Zhen Tan (Author), Reem Alshaman (Author), Imran Malik (Author), Haroon Badshah (Author), Zia Uddin (Author), Atif Ali Khan Khalil (Author), Naveed Muhammad (Author), Saifullah Khan (Author), Amjad Ali (Author), Fawad Ali Shah (Author), Jing Bo Li (Author), Shupeng Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acetaminophen (N-acetyl p-aminophenol or APAP) is used worldwide for its antipyretic and anti-inflammatory potential. However, APAP overdose sometimes causes severe liver damage. In this study, we elucidated the protective effects of carveol in liver injury, using molecular and in silico approaches....