A mouse model for inherited renal fibrosis associated with endoplasmic reticulum stress

• Main Authors: Sian E. Piret (Author), Eric Olinger (Author), Anita A. C. Reed (Author), M. Andrew Nesbit (Author), Tertius A. Hough (Author), Liz Bentley (Author), Olivier Devuyst (Author), Roger D. Cox (Author), Rajesh V. Thakker (Author)
• Format: Book
• Published: The Company of Biologists, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Renal fibrosis is a common feature of renal failure resulting from multiple etiologies, including diabetic nephropathy, hypertension and inherited renal disorders. However, the mechanisms of renal fibrosis are incompletely understood and we therefore explored these by establishing a mouse model for...