Effect and mechanism of berberine in alleviating contrast-induced nephropathy through regulating protein kinase B

• Main Authors: Ran Yu (Author), Yao Xiao (Author), Wan-peng Wang (Author), Qing-ju Li (Author), Hao-yu Chen (Author), Jian Song (Author), Jia-jia Chen (Author)
• Format: Book
• Published: Editorial Department of Journal of Clinical Nephrology, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective To explore the inhibitory effect of berberine （BBR） on contrast-induced nephropathy （CIN） and clarify the underlying mechanism. Methods Sprague-Dawley （SD） rats were utilized for constructing a rat CIN model. BBR treatment group （M+B） received a gavage of 200 mg/kg BBR while control group...