Relationship Between Cytokines in Ascites and the Severity of Ovarian Hyperstimulation Syndrome: A Case Report

Objective: Determination of the correlation of interleukin-1 (IL-1), IL-6, IL-8, tumor necrosis factor (TNF), and vascular endothelial growth factor (VEGF) levels in serum and ascites with the severity of ovarian hyperstimulation syndrome (OHSS). Case Report: We present the case of a woman with prim...

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Bibliographic Details
Main Authors: Ming-Tzeung Chung (Author), Shao-Pai Wu (Author)
Format: Book
Published: Elsevier, 2004-06-01T00:00:00Z.
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Summary:Objective: Determination of the correlation of interleukin-1 (IL-1), IL-6, IL-8, tumor necrosis factor (TNF), and vascular endothelial growth factor (VEGF) levels in serum and ascites with the severity of ovarian hyperstimulation syndrome (OHSS). Case Report: We present the case of a woman with primary infertility who was enrolled in an ovulation induction program. OHSS developed 6 days after artificial insemination with the husband's sperm. We performed continuous paracentesis and recorded daily concentrations of IL-1, IL-6, IL-8, TNF, and VEGF in serum and ascites in an attempt to determine their correlation with the severity of OHSS. Conclusion: Improvement in symptoms and a decreasing amount of ascites were correlated with a decreasing serum concentration of VEGF.
Item Description:1028-4559
10.1016/S1028-4559(09)60065-6