Regression of genital papules and mild cervical intraepithelial neoplasia during immunotherapy (clinical case)
<p> <br> </p> <p> <b>S.I. Rogovskaya<sup>1</sup>, T.N. Bebneva<sup>2,3</sup></b> </p> <p> <b><sup>1</sup>Public organization «RAGIN», Moscow, Russian Federation</b> </p> <p> <b><sup&g...
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LCC «Medicine-Inform»,
2020-06-01T00:00:00Z.
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| Summary: | <p> <br> </p> <p> <b>S.I. Rogovskaya<sup>1</sup>, T.N. Bebneva<sup>2,3</sup></b> </p> <p> <b><sup>1</sup>Public organization «RAGIN», Moscow, Russian Federation</b> </p> <p> <b><sup>2</sup>Peoples' Friendship University of Russia, Moscow, Russian Federation</b> </p> <p> <b><sup>3</sup>National Medical Research Center of Endocrinology, Moscow, Russian Federation</b> </p> <p> <i>The article is devoted to one of the most urgent problems in cervicology - diseases associated with the human papillomavirus (HPV). It is known that one of the co-risk factors for HPV persistence is a decrease in local immunity (deficiency of macrophages). The problem of cervical intraepithelial neoplasia (CIN) management is actualized by the tendency to increase this disease incidence; as a rule, the treatment of such patients consists in removing the infected tissue. Given that even after complete removal of HPV-infected tissues, CIN relapse may occur; national and foreign scientific literature increasingly focuses on auxiliary immunotherapy not only as prevention of relapses but also to stimulate the body's defences. This publication uses a clinical example to consider patient management with a clinical form of HPV infection (genital papules) and a subclinical form (mild intraepithelial lesion). Immunotherapy use in the treatment of patients with HPV-asso ciated diseases increases the efficacy of the main therapy and leads to HPV elimination.</i> </p> <p> <i><b>Keywords</b>: human papillomavirus, neoplasia, papules, LSIL, phagocyte, immunomodulator, COX-2, Polyoxidonium.</i> </p> <p> <i><b>For citation: </b>Rogovskaya S.I., Bebneva T.N. Regression of genital papules and mild cervical intraepithelial neoplasia during immunotherapy (clinical case). Russian Journal of Woman and Child Health. 2020;3(2):100-104. DOI: 10.32364/2618-8430-2020-3-2-100-104.</i> </p> |
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| Item Description: | 2618-8430 2686-7184 |