Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives
A series of histamine bis-Schiff bases and bis-spinaceamine derivatives were synthesised and investigated as activators of four human (h) carbonic anhydrase (CA, EC 4.2.1.1) isoforms, the cytosolic hCA I, II and VII, and the membrane-associated hCA IV. All isoforms were effectively activated by the...
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Main Authors: | Suleyman Akocak (Author), Nabih Lolak (Author), Silvia Bua (Author), Alessio Nocentini (Author), Claudiu T. Supuran (Author) |
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Format: | Book |
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Taylor & Francis Group,
2019-01-01T00:00:00Z.
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