Morinda officinalis iridoid glycosides, as an inhibitor of GSK-3β, alleviates rheumatoid arthritis through inhibition of NF-κB and JAK2/STAT3 pathway

• Main Authors: Yi Shen (Author), Ronghua Bao (Author), Xinyuan Ye (Author), Heming Li (Author), Yiqi Sun (Author), Qiuru Ren (Author), Jinman Du (Author), Tianwen Ye (Author), Quanlong Zhang (Author), Qiming Zhao (Author), Ting Han (Author), Luping Qin (Author), Qiaoyan Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundMorinda officinalis iridoid glycosides (MOIG) showed potential benefits in the treatment of rheumatoid arthritis (RA), but their exact mechanism has yet to be explored.PurposeTo evaluate the effects of MOIG on RA, and explore the potential targets and molecular mechanism of MOIG in RA.Meth...